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Symbol Name ID |
Wnt4
wingless-type MMTV integration site family, member 4 MGI:98957 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal external genitalia |
Aplasia of the fallopian tube |
Abnormal vagina morphology |
Aplasia of the vagina |
Abnormality of the ovary |
Aplasia of the uterus |
Hypoplasia of the uterus |
Primary amenorrhea |
| Disease(s) Associated with WNT4 | ||||||||
| Mullerian aplasia and hyperandrogenism |
| Mouse Phenotypes | reproductive system phenotype |
abnormal female germ cell morphology |
decreased oocyte number |
oocyte degeneration |
abnormal ovary morphology |
decreased mature ovarian follicle number |
absent ovary capsule |
abnormal ovary development |
decreased ovary weight |
abnormal oogenesis |
abnormal reproductive system development |
primary sex reversal |
abnormal secondary sex determination |
secondary sex reversal |
decreased litter size |
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| Availability | Mouse Genotype | |||||||||||||||
| Wnt4tm1.2Boer/Wnt4tm1.2Boer | ||||||||||||||||
| Wnt4tm1Amc/Wnt4tm1Amc | ||||||||||||||||
| Wnt4tm1Amc/Wnt4tm3(EGFP/cre)Amc | ||||||||||||||||
| Amhr2tm3(cre)Bhr/Amhr2+ Wnt4tm1.1Boer/Wnt4tm1.2Boer (conditional) |
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| Amhr2tm3(cre)Bhr/Amhr2+ Wnt4tm1Amc/Wnt4tm1.1Bhr (conditional) |
* | |||||||||||||||
| Wnt4tm2(EGFP/cre)Svo/Wnt4tm1Svo (conditional) | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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